Tissue Transglutaminase IgA (tTG-IgA) Test – At-Home Coeliac Disease Screening

Screen for Coeliac Disease with a Simple Blood Test

The Tissue Transglutaminase IgA (tTG-IgA) Test is a highly specific blood test used to screen for coeliac disease, an autoimmune disorder triggered by gluten ingestion. In coeliac disease, the immune system attacks the small intestine, producing antibodies against tissue transglutaminase, an enzyme involved in intestinal tissue repair.

Our at-home tTG-IgA blood test allows you to check for these antibodies conveniently and privately, with results analysed in UK-accredited laboratories.

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What is the Tissue Transglutaminase IgA Test?

The tTG-IgA test measures IgA antibodies against tissue transglutaminase, which are produced when the body reacts to gluten.

Key points about the test:

• Highly specific and sensitive – the most commonly recommended test for coeliac disease

• Non-invasive – requires only a small blood sample

• Useful for early detection – helps identify coeliac disease before severe intestinal damage occurs

A positive result may prompt further investigations, such as an intestinal biopsy, to confirm a diagnosis and guide treatment.

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Why Take the tTG-IgA Test?

Coeliac disease affects around 1 in 100 people in the UK, yet many cases remain undiagnosed. Untreated coeliac disease can lead to:

• Malnutrition and nutrient deficiencies

• Anaemia

• Osteoporosis and bone issues

• Fertility and pregnancy complications

• Digestive discomfort

• Increased risk of autoimmune disorders

Testing for tTG-IgA antibodies allows early detection, helping prevent long-term complications and supporting dietary or medical interventions.

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Symptoms of Coeliac Disease

Symptoms can vary and may include:

• Chronic diarrhoea or constipation

• Bloating, abdominal pain, or cramps

• Fatigue and low energy

• Unexplained weight loss

• Anaemia

• Mouth ulcers or dental enamel defects

• Skin rashes (dermatitis herpetiformis)

• Mood changes, irritability, or brain fog

Because symptoms often overlap with other conditions, blood testing is a key first step.

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Who Should Take the tTG-IgA Test?

You may benefit from testing if you:

• Experience digestive symptoms after consuming gluten

• Have a family history of coeliac disease

• Have unexplained anaemia or nutrient deficiencies

• Have osteoporosis or low bone density at an early age

• Are being monitored for known gluten sensitivity

• Are at higher risk due to autoimmune conditions such as type 1 diabetes or thyroid disorders

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How the At-Home Test Works

1. Order online – discreet, fast delivery across the UK

2. Collect your blood sample – finger-prick collection kit included

3. Return your sample – prepaid envelope to our UK-accredited laboratory

4. Receive your results online – private, secure, and easy-to-read

All samples are processed in UKAS-accredited laboratories to ensure clinical accuracy and reliability.

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Understanding Your Results

• Negative – tTG-IgA antibodies not detected, coeliac disease less likely

• Positive – antibodies present, suggesting possible coeliac disease; further testing may be required

• Borderline – may need additional follow-up

Results include clear guidance to help you interpret your antibody levels and next steps.

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Benefits of the tTG-IgA Test

• Accurate screening – highly specific for coeliac disease

• Convenient – test from home with no clinic visit needed

• Quick results – usually within 2–5 working days

• Private and confidential – secure online reporting

• Actionable insights – helps guide dietary and medical decisions

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Why Choose Repose Healthcare?

• Leading provider of at-home diagnostic testing in the UK

• Trusted UKAS-accredited laboratories

• Simple, reliable testing process

• Clear, patient-friendly reports

• Commitment to privacy and data security

Take control of your health with our tTG-IgA test and gain insights into potential gluten-related autoimmune issues.

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Order Your Tissue Transglutaminase IgA Test Today

If you suspect coeliac disease or gluten intolerance, the tTG-IgA Test provides fast, accurate results from the comfort of home. Early detection is key to managing symptoms and preventing long-term complications.

👉 Order online today – private, reliable UK lab testing delivered discreetly.