The Tissue Transglutaminase IgA (tTG-IgA) Test is a highly specific blood test used to screen for coeliac disease, an autoimmune disorder triggered by gluten ingestion. In coeliac disease, the immune system attacks the small intestine, producing antibodies against tissue transglutaminase, an enzyme involved in intestinal tissue repair.
Our at-home tTG-IgA blood test allows you to check for these antibodies conveniently and privately, with results analysed in UK-accredited laboratories.
The tTG-IgA test measures IgA antibodies against tissue transglutaminase, which are produced when the body reacts to gluten.
Key points about the test:
Highly specific and sensitive – the most commonly recommended test for coeliac disease
Non-invasive – requires only a small blood sample
Useful for early detection – helps identify coeliac disease before severe intestinal damage occurs
A positive result may prompt further investigations, such as an intestinal biopsy, to confirm a diagnosis and guide treatment.
Coeliac disease affects around 1 in 100 people in the UK, yet many cases remain undiagnosed. Untreated coeliac disease can lead to:
Malnutrition and nutrient deficiencies
Anaemia
Osteoporosis and bone issues
Fertility and pregnancy complications
Digestive discomfort
Increased risk of autoimmune disorders
Testing for tTG-IgA antibodies allows early detection, helping prevent long-term complications and supporting dietary or medical interventions.
Symptoms can vary and may include:
Chronic diarrhoea or constipation
Bloating, abdominal pain, or cramps
Fatigue and low energy
Unexplained weight loss
Anaemia
Mouth ulcers or dental enamel defects
Skin rashes (dermatitis herpetiformis)
Mood changes, irritability, or brain fog
Because symptoms often overlap with other conditions, blood testing is a key first step.
You may benefit from testing if you:
Experience digestive symptoms after consuming gluten
Have a family history of coeliac disease
Have unexplained anaemia or nutrient deficiencies
Have osteoporosis or low bone density at an early age
Are being monitored for known gluten sensitivity
Are at higher risk due to autoimmune conditions such as type 1 diabetes or thyroid disorders
Order online – discreet, fast delivery across the UK
Collect your blood sample – finger-prick collection kit included
Return your sample – prepaid envelope to our UK-accredited laboratory
Receive your results online – private, secure, and easy-to-read
All samples are processed in UKAS-accredited laboratories to ensure clinical accuracy and reliability.
Negative – tTG-IgA antibodies not detected, coeliac disease less likely
Positive – antibodies present, suggesting possible coeliac disease; further testing may be required
Borderline – may need additional follow-up
Results include clear guidance to help you interpret your antibody levels and next steps.
Accurate screening – highly specific for coeliac disease
Convenient – test from home with no clinic visit needed
Quick results – usually within 2–5 working days
Private and confidential – secure online reporting
Actionable insights – helps guide dietary and medical decisions
Leading provider of at-home diagnostic testing in the UK
Trusted UKAS-accredited laboratories
Simple, reliable testing process
Clear, patient-friendly reports
Commitment to privacy and data security
Take control of your health with our tTG-IgA test and gain insights into potential gluten-related autoimmune issues.
If you suspect coeliac disease or gluten intolerance, the tTG-IgA Test provides fast, accurate results from the comfort of home. Early detection is key to managing symptoms and preventing long-term complications.
👉 Order online today – private, reliable UK lab testing delivered discreetly.
Our home testing kits are designed to be simple, reliable, and easy to use. After placing your order, your kit will be delivered to your address with clear instructions for collecting your sample (e.g., blood, saliva, or urine or swab). Once collected, return your sample to our UKAS-accredited laboratory using the prepaid packaging. Your secure digital results will be available within 1–3 working days of the lab receiving your sample.
Yes. All tests offered by Repose Healthcare use clinically validated methods and are processed by fully accredited UK laboratories. The results are as accurate as those provided through traditional GP or private clinic services.
No. Our tests are available without the need for a prescription. They are intended for individuals who wish to proactively monitor their health in a private and convenient way.
Your results will be delivered through a secure online portal or an encrypted email, with a password sent separately to you, accompanied by easy-to-understand explanations and clear reference ranges. If any result requires clinical attention, we will guide you on appropriate next steps.
At Repose Healthcare, we prioritise your safety and peace of mind. If your results fall significantly outside the normal range, the following steps will be taken:
Our kits are suitable for adults who wish to monitor key health markers, including cholesterol, vitamin and hormone levels, blood sugar, infections, STIs, and genetic risk factors. Some tests may have age or gender-specific guidance, which will be clearly outlined on the product page.
Orders placed before 2:00pm are dispatched the same day. Kits are sent via tracked Royal Mail 24-hour service and typically arrive within 1–2 working days.
You may cancel your order for a full refund if the kit has not yet been dispatched. Once a kit has been shipped or used, we are unable to offer a refund for hygiene and regulatory reasons. If your kit arrives damaged or incomplete, please contact our customer care team within 14 days, and we will arrange a replacement at no cost.
Absolutely. Our partner laboratories are UKAS-accredited and operate under strict quality control protocols. These labs are used by both NHS and private healthcare providers, ensuring your results are handled with the highest standards.
Yes. Repose Healthcare takes data protection very seriously. We comply fully with the UK General Data Protection Regulation (UK GDPR) and all relevant data privacy laws. Your personal and medical data is encrypted, stored securely, and never shared with third parties without your explicit consent.
You can view our full Terms & Conditions, Privacy Policy, and Cookie Policy at the bottom of our website. These documents outline your rights, our responsibilities, and how we handle your data, orders, and any communications with you.